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He is also the medical director of the Spina Bifida Association of America. Brei's research has focused on healthcare outcomes for children with spina bifida and as an adult with spina bifida who is an uncommon leader, he has also served as an advocate. Brei has received extensive recognition for his work in developmental pediatrics.
Spina bifida (SB; / ˈ s p aɪ n ə ˈ b ɪ f ɪ d ə /; [9] Latin for 'split spine') [10] is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. [1] There are three main types: spina bifida occulta, meningocele and myelomeningocele. [1]
Without bowel management, the person might either suffer from the feeling of not getting relief, or they might soil themselves. [1] Bowel control is often a challenge for children who are born with anomalies in their anus or rectum, Hirschsprung's disease, and/or spina bifida. Medical providers can help anyone with long term bowel problems to ...
Subsequently, 4 medical centers conducted 253 open spina bifida repairs prior to the MOMs trial. The outcomes were mixed and the only comparison groups were other children that had not undergone repair after birth in the past. [9] In February 2003, the National Institutes of Health began the Management of Myelomeningocele Study (MOMS). Three ...
Spina bifida occulta means hidden split spine. [20] In this type of neural tube defect, the meninges do not herniate through the opening in the spinal canal. [19] The most frequently seen form of spina bifida occulta is when parts of the bones of the spine, called the spinous process, and the neural arch appear abnormal on a radiogram, without ...
Patients with spina bifida have a neural tube that has failed to completely form. This is most commonly in the lower back area in the region of the conus medullaris or cauda equina. Therefore, spina bifida affects the bowel similarly to a lower motor neuron spinal cord injury, resulting in a flaccid, unreactive rectal wall.
Risks of fetal surgery, specifically prenatal spina bifida repair, include premature rupture of membranes, uterine rupture in future pregnancies, premature birth and intraspinal inclusion cysts or a tethered cord in the fetus or newborn baby. [4] Open fetal surgery has proven to be reasonably safe for the mother. [3]
responding to the needs of adults with spina bifida and/or hydrocephalus. They do this by employing a network of advisers throughout England, Wales and Northern Ireland who deliver advice, support and advocacy services. Their staff also include specialist advisers in education, health and continence management.