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GVD is a chemotherapy regimen, used for salvage treatment of relapsed or refractory Hodgkin disease, including those patients who relapse after stem cell transplantation. [1]
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
Gemcitabine is a synthetic pyrimidine nucleoside prodrug—a nucleoside analog in which the hydrogen atoms on the 2' carbon of deoxycytidine are replaced by fluorine atoms. [ 3 ] [ 24 ] [ 25 ] The synthesis described and pictured below is the original synthesis done in the Eli Lilly Company labs.
Examples include the fluoropyrimidines, gemcitabine and platinum analogs; fluoropyrimidines increase sensitivity by dysregulating S-phase cell cycle checkpoints in tumor cells. Gemcitabine progresses through a similar mechanism, causing cells in the S-phase to disrepair DNA damage caused by the radiation.
Cisplatin is a chemical compound with formula cis-[Pt(NH 3) 2 Cl 2]. It is a coordination complex of platinum that is used as a chemotherapy medication used to treat a number of cancers . [ 3 ] These include testicular cancer , ovarian cancer , cervical cancer , bladder cancer , head and neck cancer , esophageal cancer , lung cancer ...
The prison system does not communicate with the systems used by the NHS. SystmOne is available as a number of different modules designed for different care settings. Modules for GP, prisons, child health, community units and palliative care are currently widely used throughout the NHS. In 2013, a number of secondary care modules were rolled out.
Accepting the review's recommendations, the government advised that NHS hospitals should phase out the use of the LCP over the next 6–12 months, and that "NHS England should work with clinical commissioning groups (CCGs) to bring about an immediate end to local financial incentives for hospitals to promote a certain type of care for dying ...
The Patient Advice and Liaison Service (PALS), also known as the Patient Advice and Support Service (PASS) in Scotland, is a National Health Service body created to provide advice and support to NHS patients and their relatives and carers. The scheme was announced in the NHS Plan 2000. Pilot schemes were set up in 2001, with full nationwide ...