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Eating amygdalin will cause it to release cyanide in the human body, and may lead to cyanide poisoning. [ 1 ] Since the early 1950s, both amygdalin and a chemical derivative named laetrile have been promoted as alternative cancer treatments , often under the misnomer vitamin B 17 (neither amygdalin nor laetrile is a vitamin ). [ 2 ]
Cyanide is a potent cytochrome c oxidase (COX, a.k.a. Complex IV) inhibitor, causing asphyxiation of cells. As such, cyanide poisoning is a form of histotoxic hypoxia, because it interferes with the ability of cells to take or use oxygen via oxidative phosphorylation. [25]: 1475
The amount of broken cherry pits needed to cause acute cyanide poisoning isn’t known, but adverse reactions can happen from extremely small amounts of the toxin.
Removal of cyanide from cassava in Nigeria. Cyanides are produced by certain bacteria, fungi, and algae.It is an antifeedant in a number of plants. Cyanides are found in substantial amounts in certain seeds and fruit stones, e.g., those of bitter almonds, apricots, apples, and peaches. [5]
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An apricot kernel is the apricot seed located within the fruit endocarp, which forms a hard shell around the seed called the pyrena (stone or pit). [ 1 ] [ 2 ] The kernel contains amygdalin , a poisonous compound, in concentrations that vary between cultivars.
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