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A gout flare comes on suddenly, and symptoms are often intense. This will most commonly happen at night. Gout in foot joints is most common, with gout often affecting the big toe joint.
Factors that influence rates of gout include age, race, and the season of the year. In men over 30 and women over 50, rates are 2%. [92] In the United States, gout is twice as likely in males of African descent than those of European descent. [107]
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Colchicine is typically prescribed to mitigate or prevent the onset of gout, or its continuing symptoms and pain, using a low-dose prescription of 0.6 to 1.2 mg per day, or a high-dose amount of up to 4.8 mg in the first 6 hours of a gout episode.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
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