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This is an accepted version of this page This is the latest accepted revision, reviewed on 22 December 2024. British X-ray crystallographer (1920–1958) This article is about the chemist. For the Mars rover named after her, see Rosalind Franklin (rover). Rosalind Franklin Franklin with a microscope in 1955 Born Rosalind Elsie Franklin (1920-07-25) 25 July 1920 Notting Hill, London, England ...
Photo 51 is an X-ray based fiber diffraction image of a paracrystalline gel composed of DNA fiber [1] taken by Raymond Gosling, [2] [3] a postgraduate student working under the supervision of Maurice Wilkins and Rosalind Franklin at King's College London, while working in Sir John Randall's group.
Rosalind Franklin joined King's College London in January 1951 to work on the crystallography of DNA. By the end of that year, she established two important facts: one is that phosphate groups, which are the molecular backbone for the nucleotide chains, lie on the outside (it was a general consensus at the time that they were at the inside); and the other is that DNA exists in two forms, a ...
After March 1952 Franklin concentrated on the X-ray data for the A-form of less hydrated DNA while Wilkins tried to work on the hydrated B-form. Wilkins was handicapped because Franklin had all of the good DNA. Wilkins got new DNA samples, but it was not as good as the original sample he had obtained in 1950 and which Franklin continued to use.
Francis Harry Compton Crick OM FRS [3] [4] (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist.He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the helical structure of the DNA molecule.
The film dramatises the rivalries of the two teams of scientists attempting to discover the structure of DNA: Francis Crick and James D. Watson at Cambridge University; and Maurice Wilkins and Rosalind Franklin at King's College London.
Franklin, on the other hand, rejected the first molecular model building approach proposed by Crick and Watson: the first DNA model, which in 1952 Watson presented to her and to Wilkins in London, had an obviously incorrect structure with hydrated charged groups on the inside of the model, rather than on the outside.
In the book Rosalind Franklin and DNA, author Anne Sayre is very critical of Watson's account. She claims that Watson's book did not give a balanced description of Rosalind Franklin and the nature of her interactions with Maurice Wilkins at King's College, London. Sayre's book raises doubts about the ethics of how Watson and Crick used some of ...