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Several Mycoplasma species can cause disease, including M. pneumoniae, which is an important cause of atypical pneumonia (formerly known as "walking pneumonia"), and M. genitalium, which has been associated with pelvic inflammatory diseases. Mycoplasma infections in humans are associated with skin eruptions in 17% of cases. [41]: 293
Mycoplasma hyorhinis is a species of bacteria in the Mycoplasmataceae family. It is often found as a commensal in the respiratory tract of pigs , and rarely in the skin of humans. M. hyorhinis is thought to facilitate and exacerbate the development of diseases such as porcine enzootic pneumonia and porcine reproductive and respiratory syndrome ...
It is typically associated with infection by either herpes simplex virus or Mycoplasma pneumoniae. [1] [2] [3] It is a type IV hypersensitivity reaction in which T-lymphocytes target skin keratinocytes due to the presence of specific proteins that resemble antigens of HSV, Mycoplasma, or other pathogens and foreign substances. [3]
Mycoplasma is a genus of bacteria that lack a cell wall and possess a three-layered cellular membrane. [4] They can be parasitic or saprotrophic. Several species are sexually transmitted and pathogenic in humans. Others are found on cats, dogs, and barnyard fowl.
Specific areas of research currently undertaken include mycoplasma arthritis, avian mycoplasmas, cell culture mycoplasmas, molecular genetics, phytoplasmas and ureaplasmas. The IOM also puts emphasis on pathogenesis , vaccines and mycoplasmal diseases of domestic animals and plants.
Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
Reactive arthritis, previously known as Reiter's syndrome, [1] is a form of inflammatory arthritis [2] that develops in response to an infection in another part of the body (cross-reactivity). Coming into contact with bacteria and developing an infection can trigger the disease. [ 3 ]
Thomas McPherson Brown (1906–1989) was a rheumatologist who held unorthodox views about the basis of rheumatoid arthritis (RA), and believed it could be cured with antibiotics. [ 1 ] Brown graduated from Swarthmore College then attended Johns Hopkins Medical School .