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The free radical mechanism to treat certain types of cancers extends beyond enediynes. Tirapazamine generates a free radical under anoxic conditions instead of the trigger mechanism of an enediyne. The free radical then continues on to cleave DNA in a similar manner to 1,4-didehydrobenzene in order to treat cancerous cells.
The team later assessed the concentration of these isotopes in urine samples, which correlates with the body's daily carbon dioxide production and, consequently, daily energy expenditure. [ 8 ] Results indicated that Hadza women burned an average of 1,877 calories per day, which was nearly the same as the 1,864 calories burned daily by women in ...
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
Any minor water weight usually subsides as your body adapts to a routine, and being well-hydrated is actually connected with weight loss and reduced waist circumference, per a 2021 study in ...
When working on a weight loss plan, calculating your total daily energy expenditure is often a good starting point. Understanding TDEE helps you see how various parts of your metabolism contribute ...
The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [1] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [2] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...
In living organisms, which are composed mostly of water, majority of the damage is caused by the reactive oxygen species, free radicals produced from water. The free radicals attack the biomolecules forming structures within the cells, causing oxidative stress (a cumulative damage which may be significant enough to cause the cell death, or may ...
The association between fat cell volume and changes in body weight, BMI, and total body fat remained significant when the researchers adjusted for age, physical activity, length of follow-up, and ...