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Ovarian tumours by incidence and risk of ovarian cancer, with adult granulosa cell tumour at right [7] Using next generation DNA sequencing, 97% of adult granulosa cell tumours were found to contain an identical mutation in the FOXL2 gene . This is a somatic mutation, meaning it is not usually transmitted to descendants.
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
Brenner tumours are an uncommon subtype of the surface epithelial-stromal tumour group of ovarian neoplasms. The majority are benign, but some can be malignant. [1] They are most frequently found incidentally on pelvic examination or at laparotomy. [2] Brenner tumours very rarely can occur in other locations, including the testes. [3]
A very rare tumour producing both ovarian (granulosa and/or theca) and testicular (Sertoli and/or Leydig) cells or tissues. Typically it consists of adult-type granulosa cells and Sertoli cells, [4] [5] but it has been reported with juvenile-type granulosa cells. [6] It has been reported to occur in the ovary usually, rarely in the testis. [7]
Ovarian tumors by incidence and risk of ovarian cancer, with surface epithelial-stromal tumors at top. [13] Ovarian cancers in women aged 20+, with area representing relative incidence and color representing 5-year relative survival rate. [1]
In medicine, Meigs's syndrome, also Meigs syndrome or Demons–Meigs syndrome, is the triad of ascites, pleural effusion, and benign ovarian tumor (ovarian fibroma, fibrothecoma, Brenner tumour, and occasionally granulosa cell tumour). [1] [2] [3] Meigs syndrome resolves after the resection of the tumor. Because the transdiaphragmatic lymphatic ...
The larger ovarian follicles consist of an external fibrovascular coat, connected with the surrounding stroma of the ovary by a network of blood vessels, and an internal coat, which consists of several layers of nucleated cells, called the membrana granulosa. It contains numerous granulosa cells.
Ovarian fibroma: 1.5%: 0%: Spindle-shaped fibroblastic cells and abundant collagen. [11] Adult granulosa cell tumor: 1%: Almost 100%: Small, bland, cuboidal to polygonal cells in various patterns. [12] Other sex cord-stromal tumors 1%: Others include mainly juvenile granulosa cell tumor, thecoma and sclerosing stromal tumor [5] Secondary ...
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