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  2. Amyloid plaques - Wikipedia

    en.wikipedia.org/wiki/Amyloid_plaques

    The diagnosis of Alzheimer's disease typically requires a microscopic analysis of plaques and tangles in brain tissue, usually at autopsy. [40] However, Aβ plaques (along with cerebral Aβ-amyloid angiopathy ) can be detected in the brains of living subjects by preparing radiolabeled agents that bind selectively to Aβ deposits in the brain ...

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Amyloid light chains deposition in shoulder joint causes enlarged shoulders, also known as "shoulder pad sign". [18] Amyloid light chain depositions can also cause bilateral symmetric polyarthritis. [18] The deposition of amyloid proteins in the bone marrow without causing plasma cell dyscrasias is called amyloidoma. It is commonly found in ...

  4. Cerebral amyloid angiopathy - Wikipedia

    en.wikipedia.org/wiki/Cerebral_amyloid_angiopathy

    CAA is associated with brain hemorrhages, particularly microhemorrhages.The accumulation of amyloid beta peptide deposits in the blood vessel walls results in damage of the blood vessels and hindrance of normal blood flow, making blood vessels more prone to bleeding [10] Since CAA can be caused by the same amyloid protein that is associated with Alzheimer's dementia, brain bleeds [11] are more ...

  5. List of autoimmune diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_autoimmune_diseases

    This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...

  6. Amyloid-related imaging abnormalities - Wikipedia

    en.wikipedia.org/wiki/Amyloid-related_imaging...

    Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease. ARIA is associated with anti-amyloid drugs, particularly human monoclonal antibodies such as aducanumab. [1] There are two types of ARIA: ARIA-E and ARIA-H.

  7. New study challenges amyloid-beta theory on cause for ... - AOL

    www.aol.com/study-challenges-amyloid-beta-theory...

    A main theory behind the cause of Alzheimer’s disease is the build-up of the protein amyloid-beta in the brain. Researchers from the University of Cincinnati provide evidence suggesting it’s ...

  8. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. [1] The disease is caused when a person's antibody-producing cells do not function properly and produce abnormal protein fibers made of components of antibodies called light chains. These light chains come together to form ...

  9. Organ-limited amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Organ-limited_amyloidosis

    It is contrasted to systemic amyloidosis, and it can be caused by several different types of amyloid. [1] In almost all of the organ-specific pathologies, there is debate as to whether the amyloid plaques are the causal agent of the disease or instead a downstream consequence of a common idiopathic agent. The associated proteins are indicated ...