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  2. Panitumumab - Wikipedia

    en.wikipedia.org/wiki/Panitumumab

    Panitumumab was approved by the European Medicines Agency (EMEA) in 2007, and by Health Canada in 2008, for "the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS". Panitumumab was the first monoclonal antibody to demonstrate the use of KRAS as a predictive biomarker.

  3. DailyMed - Wikipedia

    en.wikipedia.org/wiki/DailyMed

    DailyMed is a website operated by the U.S. National Library of Medicine (NLM) to publish up-to-date and accurate drug labels (also called a "package insert") to health care providers and the general public.

  4. Medication package insert - Wikipedia

    en.wikipedia.org/wiki/Medication_package_insert

    A package insert from 1970, with Ovrette brand contraception pills. A package insert is a document included in the package of a medication that provides information about that drug and its use. For prescription medications, the insert is technical, providing information for medical professionals about how to prescribe the

  5. Sotorasib - Wikipedia

    en.wikipedia.org/wiki/Sotorasib

    [4] [5] The most common adverse reactions for sotorasib used in combination with panitumumab include rash, dry skin, diarrhea, stomatitis, fatigue, and musculoskeletal pain. [ 4 ] [ 9 ] Sotorasib is the first approved targeted therapy for people with tumors with any KRAS mutation, which accounts for approximately 25% of mutations in non-small ...

  6. An overlooked corner of the Trump trade is up more than 100% ...

    www.aol.com/overlooked-corner-trump-trade-more...

    Fannie and Freddie, which buy mortgages and package them into bonds to sell to investors, are a crucial source of liquidity for the mortgage market and allow lenders to keep making new loans.

  7. Cetuximab - Wikipedia

    en.wikipedia.org/wiki/Cetuximab

    Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. [2]

  8. Obinutuzumab - Wikipedia

    en.wikipedia.org/wiki/Obinutuzumab

    Obinutuzumab has two black box warnings: hepatitis B reactivation and progressive multifocal leukoencephalopathy. [7] [5]In the clinical trial of obinutuzumab in combination with chlorambucil, participants experienced infusion reactions (69%; 21% grade 3/4), neutropenia (40%; 34% grade 3/4), thrombocytopenia (15%; 11% grade 3/4), anemia (12%), and pyrexia and cough (10% each).

  9. Afatinib - Wikipedia

    en.wikipedia.org/wiki/Afatinib

    Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC). [2] [3] [4] It belongs to the tyrosine kinase inhibitor family of medications. [5]