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  2. Endocardial cushions - Wikipedia

    en.wikipedia.org/wiki/Endocardial_cushions

    Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa. They develop on the atrioventricular canal [2] and conotruncal region of the bulbus cordis. [3] During heart development, the heart starts out as a tube. As heart ...

  3. Endocardium - Wikipedia

    en.wikipedia.org/wiki/Endocardium

    Illustration depicting the layers of the heart wall including the innermost endocardium. The endocardium (pl.: endocardia) is the innermost layer of tissue that lines the chambers of the heart. Its cells are embryologically and biologically similar to the endothelial cells that line blood vessels. The endocardium also provides protection to the ...

  4. Protein signalling in heart development - Wikipedia

    en.wikipedia.org/wiki/Protein_signalling_in...

    Migration of cardiac precursor cells and fusion of the primordia: The cardiac precursor cells migrate anteriorly towards the midline and fuse into a single heart tube. Fibronectin in the extracellular matrix directs this migration. If this migration event is blocked, cardia bifida results where the two heart primordia remain separated. During ...

  5. Cardiac excitation-contraction coupling - Wikipedia

    en.wikipedia.org/wiki/Cardiac_excitation...

    These cells, unlike most other cells within the heart, can spontaneously produce action potentials. [5] These action potentials travel along the cell membrane (sarcolemma) , as impulses, passing from one cell to the next through channels, in structures known as gap junctions .

  6. Purkinje fibers - Wikipedia

    en.wikipedia.org/wiki/Purkinje_fibers

    Purkinje fibers take up stain differently from the surrounding muscle cells because of having relatively fewer myofibrils than other cardiac cells. The presence of glycogen around the nucleus causes Purkinje fibers to appear, on a slide, lighter and larger than their neighbors, being arranged along the longitudinal direction (parallel to the ...

  7. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    The initiation of endochondral ossification starts by proliferation and condensation of mesenchymal cells in the area where the bone will eventually be formed. Subsequently, these mesenchymal progenitor cells differentiate into chondroblasts, which actively synthesize cartilage matrix components. Thus, the initial hyaline cartilage template is ...

  8. Ventricular remodeling - Wikipedia

    en.wikipedia.org/wiki/Ventricular_remodeling

    The cardiac myocyte is the major cell involved in remodeling. Fibroblasts, collagen, the interstitium, and the coronary vessels to a lesser extent, also play a role. A common scenario for remodeling is after myocardial infarction. There is myocardial necrosis (cell death) and disproportionate thinning of the heart. This thin, weakened area is ...

  9. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The cardiomyocytes make up the bulk (99%) of cells in the atria and ventricles. These contractile cells respond to impulses of action potential from the pacemaker cells and are responsible for the contractions that pump blood through the body. The pacemaker cells make up just (1% of cells) and form the conduction system of the heart.

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