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Testicular cancer is highly treatable and usually curable. [5] Treatment options may include surgery, radiation therapy, chemotherapy, or stem cell transplantation. [2] Even in cases in which cancer has spread widely, chemotherapy offers a cure rate greater than 80%. [4] Globally testicular cancer affected about 686,000 people in 2015. [6]
Leydig cell tumour, also Leydig cell tumor (US spelling), (testicular) interstitial cell tumour and (testicular) interstitial cell tumor (US spelling), is a member of the sex cord-stromal tumour group [2] of ovarian and testicular cancers. It arises from Leydig cells. While the tumour can occur at any age, it occurs most often in young adults.
The body has a central vessel surrounded by fibrous tissue, called the fibrovascular core, and it is surrounded by layers of the tumoral cells at the surface of that stalk. The structure is located in open cystic space also lined by tumoral cells. All those structures together are called a Schiller–Duval body and resemble primitive glomerulus.
Symptoms of testicular cancer can include a bump on a testicle or a swollen testicle, according to the American Cancer Society. Often, signs do not develop until the cancer is more advanced, the ...
It is the most common testicular cancer of non-germ cell origin. [13] Sonography may be used to identify cystic areas, but it is unable to tell benign tumours apart from malignant tumours. [13] Adrenomyeloneuropathy is another example of a disease affecting the Leydig cell. [14]
In humans, this group accounts for 8% of ovarian cancers and under 5% of testicular cancers. Their diagnosis is histological: only a biopsy of the tumour can make an exact diagnosis. Their diagnosis is histological: only a biopsy of the tumour can make an exact diagnosis.
Relative incidences of testicular tumors, showing seminoma at bottom left. [2] A seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages. [3]
Germ cells tumors constitute a vast majority of the incidences of testicular tumors. [3]GCTs are classified by their histology, [4] regardless of location in the body. . However, as more information about the genetics of these tumors become available, they may be classified based on specific gene mutations that characterize specific tu