Ads
related to: side effects of docetaxel chemo- Dosing & Administration
View Dosing Charts
Study Dosing Information Here
- Efficacy & Safety
Adverse Reactions Of Interest
Common Reactions Table
- HER2+ mCRC Testing
Learn How To Test
Learn When to Test
- Clinical Study
Trial Design and Endpoints
Inlcusion Criteria Here
- Dosing & Administration
cancer.osu.edu has been visited by 10K+ users in the past month
Search results
Results From The WOW.Com Content Network
[12] [25] As with all chemotherapy, adverse effects are common, and many side effects have been documented. [17] [19] Because docetaxel is a cell-cycle-specific agent, it is cytotoxic to all dividing cells in the body. [26] This includes tumour cells as well as hair follicles, bone marrow and other germ cells.
In 1983, Coates et al. found that people receiving chemotherapy ranked nausea and vomiting as the first and second most severe side-effects, respectively. [98] Up to 20% of people receiving highly emetogenic agents in this era postponed, or even refused potentially curative treatments. [ 99 ]
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Docetaxel, is a semi-synthetic analogue of paclitaxel, with a trade name Taxotere. Docetaxel has the minimal structure modifications at C13 side chain and C10 substitution showed more water solubility and more potency than paclitaxel.
Chemotherapy for NSCLC usually includes combination of two drugs (chemotherapy doublet), with one of the agents is cisplatin or carboplatin. In 2002, Schiller at al. published in the New England Journal of Medicine, a study that compared four chemotherapy regimens for advanced NSCLC, cisplatin and paclitaxel, cisplatin and gemcitabine, cisplatin and docetaxel, and carboplatin and paclitaxel. [14]
Sensory side effects include paresthesias, dysesthesias, numbness, altered proprioception, and loss of dexterity in fingers and toes. Motor and autonomic symptoms are less frequent but possible. Symptoms may start days after the patient receives their first dose of chemotherapy, are dose dependent, and tend to improve after completion of treatment.
Ad
related to: side effects of docetaxel chemo