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Paraxanthine is the primary metabolite of caffeine in humans and other animals, such as mice. [3] Shortly after ingestion, roughly 84% of caffeine is metabolized into paraxanthine by hepatic cytochrome P450, which removes a methyl group from the N3 position of caffeine.
Caffeine is metabolized in the liver into three primary metabolites: paraxanthine (84%), theobromine (12%), and theophylline (4%) [citation needed] Even without dietary intake, theobromine may occur in the body as it is a product of the human metabolism of caffeine , which is metabolised in the liver into 12% theobromine, 4% theophylline , and ...
Caffeine's biological half-life – the time required for the body to eliminate one-half of a dose – varies widely among individuals according to factors such as pregnancy, other drugs, liver enzyme function level (needed for caffeine metabolism) and age.
Salmon. This fatty fish is one of nature’s best sources of omega-3s. A 2023 study published in the Journal of the American Heart Association found that consuming 2 grams of EPA and DHA—the two ...
Olive oil Extra-virgin olive oil is a staple of the MIND and Mediterranean diets because it provides monounsaturated fat, omega-3s, and antioxidant-rich vitamin E that science shows can be ...
Low levels of vitamin B12 are common, ... Vitamin D is present in a limited number of foods—fatty fish and cod liver oil are some of the best food sources. ... catechins and caffeine, ...