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  2. Half-life - Wikipedia

    en.wikipedia.org/wiki/Half-life

    In this situation it is generally uncommon to talk about half-life in the first place, but sometimes people will describe the decay in terms of its "first half-life", "second half-life", etc., where the first half-life is defined as the time required for decay from the initial value to 50%, the second half-life is from 50% to 25%, and so on.

  3. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (C max) to half of C max in the blood plasma.

  4. Exponential decay - Wikipedia

    en.wikipedia.org/wiki/Exponential_decay

    The biological half-lives "alpha half-life" and "beta half-life" of a substance measure how quickly a substance is distributed and eliminated. Physical optics: The intensity of electromagnetic radiation such as light or X-rays or gamma rays in an absorbent medium, follows an exponential decrease with distance into the absorbing medium.

  5. Effective half-life - Wikipedia

    en.wikipedia.org/wiki/Effective_half-life

    Alternatively, since the radioactive decay contributes to the "physical (i.e. radioactive)" half-life, while the metabolic elimination processes determines the "biological" half-life of the radionuclide, the two act as parallel paths for elimination of the radioactivity, the effective half-life could also be represented by the formula: [1] [2]

  6. Radioactive decay - Wikipedia

    en.wikipedia.org/wiki/Radioactive_decay

    The half-life, t 1/2, is the time taken for the activity of a given amount of a radioactive substance to decay to half of its initial value. The decay constant , λ " lambda ", the reciprocal of the mean lifetime (in s −1 ), sometimes referred to as simply decay rate .

  7. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level , but this also means that, without an initial higher dose, it would take a long ...

  8. Doubling time - Wikipedia

    en.wikipedia.org/wiki/Doubling_time

    The doubling time is a characteristic unit (a natural unit of scale) for the exponential growth equation, and its converse for exponential decay is the half-life. As an example, Canada's net population growth was 2.7 percent in the year 2022, dividing 72 by 2.7 gives an approximate doubling time of about 27 years.

  9. Plateau principle - Wikipedia

    en.wikipedia.org/wiki/Plateau_Principle

    Half-life has units of time, and the elimination rate constant has units of 1/time, e.g., per hour or per day. An equation can be used to forecast the concentration of a compound at any future time when the fractional degration rate and steady state concentration are known: