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The subtypes of influenza A virus are estimated to have diverged 2,000 years ago. Influenza viruses A and B are estimated to have diverged from a single ancestor around 4,000 years ago, while the ancestor of influenza viruses A and B and the ancestor of influenza virus C are estimated to have diverged from a common ancestor around 8,000 years ago.
Influenza A virus structure. The influenzavirus virion is pleomorphic; the viral envelope can occur in spherical and filamentous forms. In general, the virus's morphology is ellipsoidal with particles 100–120 nm in diameter, or filamentous with particles 80–100 nm in diameter and up to 20 μm long. [5]
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses.Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue.
3D model of the flu virion. (M2 labeled in white.) The Matrix-2 (M2) protein is a proton-selective viroporin, integral in the viral envelope of the influenza A virus. The channel itself is a homotetramer (consists of four identical M2 units), where the units are helices stabilized by two disulfide bonds, and is activated by low pH.
The G4 virus, also known as the "G4 swine flu virus" (G4) and "G4 EA H1N1", is a swine influenza virus strain discovered in China. [68] The virus is a variant genotype 4 (G4) Eurasian avian-like (EA) H1N1 virus that mainly affects pigs, but there is some evidence of it infecting people. [ 68 ]
There are four different types of influenza virus: A, B, C, and D. Influenza C usually causes only mild illness while D mostly affects animals, especially cattle.
Influenza viruses: You’re likely familiar with the seasonal flu, but in the last century there have also been four influenza pandemics: the infamous Spanish Flu pandemic in 1918, the H2N2 flu ...
The genetic structure of H5N1, a highly pathogenic avian influenza virus (influenza A virus subtype H5N1), is characterized by a segmented RNA genome consisting of eight gene segments that encode for various viral proteins essential for replication, host adaptation, and immune evasion.
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