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β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
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Tesofensine has a long half-life of about 9 days (220 h) [4] "and is mainly metabolized by cytochrome P4503A4 to its desalkyl metabolite M1" NS2360. [10] [11] NS2360 is the only metabolite detectable in human plasma.
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