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Rheumatology. Sarcopenia (ICD-10 code M62.84) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors. The muscle loss is related to changes ...
Osteopenia. Osteopenia, known as " low bone mass " or " low bone density ", is a condition in which bone mineral density is low. [1] Because their bones are weaker, people with osteopenia may have a higher risk of fractures, and some people may go on to develop osteoporosis. [2] In 2010, 43 million older adults in the US had osteopenia. [3]
As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...
A basal central:peripheral ratio of over 2:1, or a ratio over 3:1 when CRH is administered, is indicative of Cushing's disease. [8] This test has been the gold standard for distinguishing between Cushing's disease and ectopic corticotropin syndrome, [ 8 ] with a sensitivity and specificity of 94% for Cushing's disease, [ 11 ] and a very low ...
Stigmata. Stigmata (Ancient Greek: στίγματα, plural of στίγμα stigma, 'mark, spot, brand'), in Catholicism, are bodily wounds, scars and pain which appear in locations corresponding to the crucifixion wounds of Jesus Christ: the hands, wrists, feet, near the heart, the head (from the crown of thorns), and back (from carrying the ...
Renal osteodystrophy is currently defined as an alteration of bone morphology in patients with chronic kidney disease (CKD). [1] It is one measure of the skeletal component of the systemic disorder of chronic kidney disease-mineral and bone disorder (CKD-MBD). [1][2][3] The term "renal osteodystrophy" was coined in 1943, [4] 60 years after an ...
Aromatase deficiency is a rare condition characterized by extremely low levels or complete absence of the enzyme aromatase activity in the body. [2] It is an autosomal recessive disease resulting from various mutations of gene CYP19 (P450arom) which can lead to ambiguous genitalia and delayed puberty in females, continued linear growth into adulthood and osteoporosis in males and virilization ...
Sarcopenic obesity is a combination of two disease states, sarcopenia and obesity. Sarcopenia is the muscle mass/strength/physical function loss associated with increased age, [1] and obesity is based off a weight to height ratio or body mass index (BMI) that is characterized by high body fat or being overweight. [2] The risk of sarcopenic ...