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Phytomenadione, also known as vitamin K 1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] It is used to treat certain bleeding disorders, [7] including warfarin overdose, vitamin K deficiency, and obstructive jaundice. [7]
Vitamin K is a family of structurally similar, fat-soluble vitamers found in foods and marketed as dietary supplements. [1] The human body requires vitamin K for post-synthesis modification of certain proteins that are required for blood coagulation ("K" from Danish koagulation, for "coagulation") or for controlling binding of calcium in bones and other tissues. [2]
Newborn infants have low stores of vitamin K, and human breast milk has low concentrations of the vitamin. This combination can lead to vitamin K deficiency and later onset bleeding. Vitamin K deficiency leads to the risk of blood coagulation problems due to impaired production of clotting factors II, VII, IX, X, protein C and protein S by the ...
The menadione core is apparent in the structure of vitamin K. It is an intermediate in the chemical synthesis of vitamin K by first reduction to the diol menadiol, which is susceptible to coupling to the phytol. [10] It is a useful intermediate for organic synthesis in general, as it can be made and modified in a number of ways. [11]
Vitamin K 1-deficiency may occur by disturbed intestinal uptake (such as would occur in a bile duct obstruction), by therapeutic or accidental intake of a vitamin K 1-antagonist such as warfarin, or, very rarely, by nutritional vitamin K 1 deficiency. As a result, Gla-residues are inadequately formed and the Gla-proteins are insufficiently active.
[2] [3] Vitamin K injections are administered to newborns as a preventative measure to reduce the risk of hemorrhagic disease of the newborn (HDN). [ 4 ] [ 5 ] The coagulation pathway helps the body stop active bleeds by using vitamin K dependent clotting factors (factors II, VII, IX, and X) which are synthesized by the liver.
Golden Retriever puppy Basset Hound Newborn Welsh Springer Spaniels. A puppy is a juvenile dog, generally one less than 12-18 months old. Puppies are markedly underdeveloped and dependent on their mothers at birth (displaying altriciality), but healthy puppies grow quickly and begin walking thereafter. Puppies generally weigh 8–16 oz (0.23 ...
T.K Group's brands have secured the heart of the people of Bangladesh for a few decades. This group has been awarded many awards nationally and internationally since its journey began. It has been awarded many times as "Standard Chartered Trade Awards", [ 17 ] "Best Brand Award" [ 18 ] for the contribution to the growth of the country's export ...