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The word zygosity may also be used to describe the genetic similarity or dissimilarity of twins. [6] Identical twins are monozygotic, meaning that they develop from one zygote that splits and forms two embryos. Fraternal twins are dizygotic because they develop from two separate oocytes (egg cells) that are fertilized by two separate sperm.
The cause of the condition lies in conception or utero with the aggregation of two distinct zygotes or blastocysts (one of which expresses 46,XX and the other of which expresses 46,XY) into a single embryo, [4] which subsequently leads to the development of a single individual with two distinct cell lines, instead of a pair of fraternal twins.
The human twin birth rate in the United States rose 76% from 1980 through 2009, from 9.4 to 16.7 twin sets (18.8 to 33.3 twins) per 1,000 births. [5] The Yoruba people have the highest rate of twinning in the world, at 45–50 twin sets (90–100 twins) per 1,000 live births, [6] [7] [8] possibly because of high consumption of a specific type of yam containing a natural phytoestrogen which may ...
The power of twin designs arises from the fact that twins may be either identical (monozygotic (MZ), i.e. developing from a single fertilized egg and therefore sharing all of their polymorphic alleles) or fraternal (dizygotic (DZ), i.e. developing from two fertilized eggs and therefore sharing on average 50% of their alleles, the same level of genetic similarity found in non-twin siblings).
The use of twins can improve the statistical power of a genetic study by reducing the amount of genetic and/or environmental variability. [1] " Identical twins" (monozygotic (MZ) twins) share virtually all their genes with each other, and "fraternal twins" (dizygotic (DZ) twins), on average, share about 50% of their genes with each other (about the same amount of sharing as non-twin siblings).
Fraternal twins develop from two different eggs by two different sperm -- so they can often look slightly different. Although some, like Mary Kate and Ashley Olsen, end up looking so much alike ...
Identical twins of the ‘Ask Reddit’ community recently shared what are the main differences between them and their sibling, showing that the dissimilarities can range from a unique mole to one ...
Dizygotic (fraternal) twins can be caused by a hyperovulation gene in the mother. [8] Although the father's genes do not influence the woman's chances of having twins, he could influence his children's chances of having twins by passing on a copy of the hyperovulation gene to them. Monozygotic (identical) twins do not run in families.