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Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. [1] [2] If there is decreased secretion of one specific pituitary hormone, the condition is known as selective hypopituitarism. [3]
The syndrome of inappropriate antidiuretic hormone secretion (SIADH), also known as the syndrome of inappropriate antidiuresis (SIAD), [2] is characterized by a physiologically inappropriate release of antidiuretic hormone (ADH) either from the posterior pituitary gland, or an abnormal non-pituitary source. [1]
Nephrogenic DI may be treated by addressing the underlying cause or by the use of a thiazide, aspirin or ibuprofen. [1] The number of new cases of diabetes insipidus each year is 3 in 100,000. [4] Central DI usually starts between the ages of 10 and 20 and occurs in males and females equally. [2] Nephrogenic DI can begin at any age. [3]
Outcomes are typically good when treated. Most people can expect to live relatively normal lives. Someone with the disease should be observant of symptoms of an "Addison's crisis" while the body is strained, as in rigorous exercise or being sick, the latter often needing emergency treatment with intravenous injections to treat the crisis. [11]
Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone .
Patients with adrenocorticotropic hormone deficiency typically do well during non-stressful periods until an intervening event triggers an acute adrenal crisis. This life-threatening illness is characterized by extreme fatigue , acute abdominal pain , nausea , vomiting , diarrhea , fever , severe hypotension , and hypoglycemia , and may be ...
Sheehan's syndrome typically occurs because of excessive blood loss after delivery (post-partum hemorrhage), although there are several risk factors that may contribute to its development. [9] This syndrome does not appear to be exclusively linked to childbirth, as Sheehan's syndrome has been reported in pregnant patients that experienced ...
Oxytocin is typically used right after the delivery of the baby to prevent PPH. [2] Misoprostol may be used in areas where oxytocin is not available. [2] Early clamping of the umbilical cord does not decrease risks and may cause anemia in the baby, and thus is usually not recommended. [2]