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Chronic eosinophilic leukemia is a form of cancer in which too many eosinophils are found in the bone marrow, blood, and other tissues.
Acute eosinophilic leukemia (AEL) is a rare subtype of acute myeloid leukemia with 50 to 80 percent of eosinophilic cells in the blood and marrow. It can arise de novo or may develop in patients having the chronic form of a hypereosinophilic syndrome .
Types of eosinophilic leukemia include: Chronic eosinophilic leukemia; Acute eosinophilic leukemia; Clonal eosinophilia This page was last edited on 11 May 2022 ...
Clonal hypereosinophilia, also termed primary hypereosinophilia or clonal eosinophilia, is a grouping of hematological disorders all of which are characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow, blood, and other tissues.
Acute promyelocytic leukemia was first characterized in 1957 [4] [5] by French and Norwegian physicians as a hyperacute fatal illness, [3] with a median survival time of less than a week. [6] Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study. [7] [6] [8]
At least one case of FIP1L1-PDGFRA fusion gene-induced eosinophilic leukemia presenting with myeloid sarcoma and eosinophilia has been reported. This form of myeloid sarcoma is distinguished by its highly successful treatment with imatinib (the recommended treatment for FIP1L1-PDGRGA fusion gene-induced eosinophilic leukemia) rather than more aggressive and toxic therapy.