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Complex post-traumatic stress disorder (CPTSD, cPTSD, or hyphenated C-PTSD) is a stress-related mental and behavioral disorder generally occurring in response to complex traumas [1] (i.e., commonly prolonged or repetitive exposures to a series of traumatic events, from which one sees little or no chance to escape). [2] [3] [4]
Prolonged exposure has been beneficial for those with co-occurring PTSD and substance abuse when combined with substance abuse treatment. [8] Studies have also reflected that prolonged exposure therapy aids patients who have both PTSD and borderline personality disorder when the treatment is coupled with dialectical behavior therapy. [3]
Evidence-based, trauma-focused psychotherapy is the first-line treatment for PTSD. [8] [9] [6] Psychotherapy is defined as a treatment where a therapist and patient build a therapeutic relationship and focus on the patient's thoughts, attitudes, affect, behavior, and social development to lessen the patient's psychopathologies and functional impairment.
The FDA, which approved the protocols for the studies it now questions, is asking for an additional Phase 3 clinical trial, which would take years and millions of dollars.
PTSD is a disorder caused by very stressful events and can significantly disrupt patients' lives. US FDA panel to discuss first psychedelic-assisted PTSD treatment next month (May 6) Skip to main ...
A phase III study indicated that MDMA-assisted therapy represents a potential breakthrough treatment for severe PTSD that merits expedited clinical evaluation. [17] Based on this study, MDMA-assisted psychotherapy was granted breakthrough therapy designation by the FDA, a designation that indicates that there is preliminary evidence that an intervention might offer a substantial improvement ...