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An example of an algorithm for determining the indication for prenatal genetic testing for trisomy 21 (Down syndrome), wherein the genetic blood test (in center) is performed by detecting cffDNA in a blood sample from the mother. [60] Trisomy 21. Fetal trisomy of chromosome 21 is the cause of Down's syndrome.
Non-invasive prenatal genetic screening is typically performed at the end of the 1st trimester (11–14 weeks) or during the beginning of the second trimester (15–20 weeks). This involves the pregnant woman receiving a blood draw with a needle and a syringe and an ultrasound of the fetus.
An increase in vaginal discharge is common during pregnancy due to hormonal changes. The discharge, known as leukorrhea, is usually thin and milky white. However, if the discharge changes color or consistency significantly, it is essential to consult a healthcare provider. [9]
Normal vaginal discharge is composed of cervical mucus, vaginal fluid, shedding vaginal and cervical cells, and bacteria. [1] The majority of the liquid in vaginal discharge is mucus produced by glands of the cervix. [1] [4] The rest is made up of transudate from the vaginal walls and secretions from glands (Skene's and Bartholin's). [4]
Leukorrhea can be confirmed by finding >10 WBC per high-power field under a microscope when examining vaginal fluid. [6] Vaginal discharge is normal, and causes of change in discharge include infection, malignancy, and hormonal changes. It sometimes occurs before an adolescent female has her first period, and is considered a sign of puberty.
Women’s health expert Dr. Jennifer Wider tells Yahoo Life that “weeks 5 to 9 is the early time period in a pregnancy. At 5 weeks, the embryo is a mass of cells with a developing neural tube ...
Chorionic villi are projections from the placenta that carry the same genetic makeup as the baby. During this method of prenatal testing, a sample of chorionic villi is removed from the placenta to be tested. This test is performed 10–13 weeks into pregnancy and results are ready 7–14 days after the test was done. [18]
Tobacco use during pregnancy [10] Illicit drug use during pregnancy [11] Having had PROM or preterm delivery in previous pregnancies [8] Polyhydramnios: too much amniotic fluid [9] Multiple gestation: being pregnant with two or more fetuses at one time [8] Having had episodes of bleeding anytime during the pregnancy [8]