When.com Web Search

Search results

  1. Results From The WOW.Com Content Network
  2. Hypothalamic–pituitary–adrenal axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    Schematic of the HPA axis (CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone) Hypothalamus, pituitary gland, and adrenal cortex The hypothalamic–pituitary–adrenal axis (HPA axis or HTPA axis) is a complex set of direct influences and feedback interactions among three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a ...

  3. Cortisone reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Cortisone_reductase_deficiency

    Dysregulation of hexose-6-phosphate dehydrogenase occurs as a result of gene mutation. [12] Cortisol is important in signalling inhibition of adrenocorticotropic hormone release from the pituitary. Reduced cortisol in circulation activates the H-P-A Axis to produce and release more cortisol, and therefore androgen.

  4. Critical illness–related corticosteroid insufficiency - Wikipedia

    en.wikipedia.org/wiki/Critical_illness–related...

    The hypothalamic-pituitary-adrenal axis (HPA axis), in which the hypothalamus and pituitary gland control adrenal secretions, undergoes profound changes during critical illness. Both very high and very low levels of cortisol have been linked to a poor outcome in intensive care patients. [ 2 ]

  5. Post-traumatic stress disorder - Wikipedia

    en.wikipedia.org/wiki/Post-traumatic_stress_disorder

    The HPA axis is responsible for coordinating the hormonal response to stress. [61] Given the strong cortisol suppression to dexamethasone in PTSD, HPA axis abnormalities are likely predicated on strong negative feedback inhibition of cortisol, itself likely due to an increased sensitivity of glucocorticoid receptors. [121]

  6. Allostatic load - Wikipedia

    en.wikipedia.org/wiki/Allostatic_load

    The Hypothalamic–pituitary–adrenal axis is the central stress response system responsible for the modification of inflammatory responses throughout the body. Prolonged stress levels can lead to decreased levels of cortisol in the morning and increased levels in the afternoon, leading to greater daily output of cortisol which in the long ...

  7. Sympathoadrenal system - Wikipedia

    en.wikipedia.org/wiki/Sympathoadrenal_system

    The stress induced during exercise results in an increase in the hormones, epinephrine and norepinephrine, which are known for the body's "fight or flight" response. Increased secretion of catecholamines are a hormone response regulated by the sympathoadrenal system (SAS) and the hypothalamic-pituitary-adrenal axis (HPAA). [10]

  8. Corticotropic cell - Wikipedia

    en.wikipedia.org/wiki/Corticotropic_cell

    Corticotropic cells can have detrimental effects on the body if they express too much or too little ACTH. One such example is Cushing's disease , which can result from overproduction of ACTH in the corticotropes due to pituitary tumors known as corticotroph adenomas ; this is the cause for roughly two-thirds of those diagnosed with Cushing's ...

  9. Post-stroke depression - Wikipedia

    en.wikipedia.org/wiki/Post-stroke_depression

    HPA axis dysfunction is associated with both sustained elevation of glucocorticoid levels and chronic inflammation, both of which are associated with major depressive disorder. [11] Dysregulation of the HPA axis can perpetuate a cycle of neuroinflammation that exacerbates depressive symptoms.