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Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.
Copper toxicity (or Copperiedus) is a type of metal poisoning caused by an excess of copper in the body. Copperiedus could occur from consuming excess copper salts, but most commonly it is the result of the genetic condition Wilson's disease and Menke's disease, which are associated with mismanaged transport and storage of copper ions.
Alpha lipoic acid (ALA) is an antioxidant that is made naturally by human cells. [50] It can also be administered in capsules or can be found in foods such as red meat, organ meats, and yeast. [50] Like other antioxidants, it functions by ridding the body of harmful free radicals that can cause damage to tissues and organs. [50]
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Alpha-lipoic acid [87] [88] Weight gain: Well tolerated: 1 DB-RPCT: 360: Offset antipsychotic drug-induced weight gain. Increased total antioxidant status. May also increase GSH:GSSG (reduced glutathione:oxidized glutathione) ratio. [89] L-Theanine [90] [91] [92] Positive, activation, and anxiety symptoms: Well tolerated: 2 DB-RPCTs: 40 ...
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
Opioids, while commonly used in chronic neuropathic pain, are not a recommended first or second line treatment. [33] In the short and long term they are of unclear benefit, although clinical experience suggests that opioids like tramadol may be useful for treating sudden onset severe pain [ 34 ] In the intermediate term evidence of low quality ...
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