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  2. Dorzolamide - Wikipedia

    en.wikipedia.org/wiki/Dorzolamide

    Dorzolamide, developed by Merck, was the first medication in human therapy (market introduction 1995) that resulted from structure-based drug design. It was developed to circumvent the systemic side effects of acetazolamide which has to be taken orally.

  3. Intravitreal administration - Wikipedia

    en.wikipedia.org/wiki/Intravitreal_administration

    Severe inflammation can cause permanent damage to the eye. The risk of inflammation varies based on the specific drug being administered. One clinical trial of ranibizumab for age-related macular degeneration administered intravitreally reported intraocular inflammation rates between 1.4% and 2.9%.

  4. Intravitreal injection - Wikipedia

    en.wikipedia.org/wiki/Intravitreal_injection

    Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]

  5. Choroidal neovascularization - Wikipedia

    en.wikipedia.org/wiki/Choroidal_neovascularization

    Layers of the eye, with the choroid labelled. Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye.Choroidal neovascularization is a common cause of neovascular degenerative maculopathy (i.e. 'wet' macular degeneration) [1] commonly exacerbated by extreme myopia, malignant myopic degeneration, or age-related developments.

  6. Diabetic retinopathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_retinopathy

    Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.

  7. Vitreomacular adhesion - Wikipedia

    en.wikipedia.org/wiki/Vitreomacular_adhesion

    The pulling forces or traction from this adhesion on the retinal surface can sometimes cause edema within the retina, damage to retinal blood vessels causing bleeding, or damage to the optic nerve causing disruption in the nerve signals sent to the brain for visual processing. It is important to note that while the VMA itself is not dangerous ...

  8. Retinopathy - Wikipedia

    en.wikipedia.org/wiki/Retinopathy

    Retinopathy is any damage to the retina of the eyes, which may cause vision impairment. [1] Retinopathy often refers to retinal vascular disease, or damage to the retina caused by abnormal blood flow. [2] Age-related macular degeneration is technically

  9. Macular scarring - Wikipedia

    en.wikipedia.org/wiki/Macular_scarring

    Macular scarring is formation of the fibrous tissue in place of the normal retinal tissue on the macular area of the retina which provides the sharpest vision in the eyes. It is usually a result of an inflammatory or infectious process. [1] Other etiologies include macular pucker (macular detachment), macular hole, and age-related macular ...

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