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The trophoblast (from Greek trephein: to feed; and blastos: germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. [ 1 ] They provide nutrients to the embryo and develop into a large part of the placenta .
"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there.It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo.
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
The epiblast gives rise to the three germ layers of the developing embryo during gastrulation (endoderm, mesoderm, and ectoderm). The trophoblast is a layer of cells forming the outer ring of the blastocyst that combines with the maternal endometrium to form the placenta. Trophoblast cells also secrete factors to make the blastocoel. [25]
A common feature of a vertebrate blastula is that it consists of a layer of blastomeres, known as the blastoderm, which surrounds the blastocoel. [ 4 ] [ 5 ] In mammals , the blastocyst contains an embryoblast (or inner cell mass) that will eventually give rise to the definitive structures of the fetus , and a trophoblast which goes on to form ...
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The chorion consists of two layers: an outer formed by the trophoblast, and an inner formed by the extra-embryonic mesoderm. The trophoblast is made up of an internal layer of cubical or prismatic cells, the cytotrophoblast or layer of Langhans, and an external multinucleated layer, the syncytiotrophoblast .