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The basal ganglia (BG) or basal nuclei are a ... is then free to inhibit the thalamus. This pathway consists ... of the indirect pathways. [29] Diagram shows two ...
English: Connection diagram of the basal ganglia. Glutamatergic pathways are red, dopaminergic pathways are magenta and GABAergic pathways are blue. GPe = Globus Pallidus external; GPi = Globus Pallidus internal; STN = SubThalamic Nucleus; SNpr = Pars Reticulata portion of Substantia Nigra; SNpc = Pars Compacta portion of Substantia Nigra
English: Circuits of the basal ganglia. Picture shows 2 coronal slices that have been superimposed to include the involved basal ganglia structures. + and - signs at the point of the arrows indicate respectively whether the pathway is excitatory or inhibitory in effect.
Anatomical overview of the main circuits of the basal ganglia. Subthalamic nucleus is shown in red. Picture shows 2 coronal slices that have been superimposed to include the involved basal ganglia structures. + and - signs at the point of the arrows indicate respectively whether the pathway is excitatory or inhibitory in effect.
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Original in raster (.png) format - Main circuits of the basal ganglia Original in vector (.svg) format (The brain images at top are imported raster). Reason It explains the circuits of the basal ganglia in an anatomically precise and almost artistic manner, facilitating the understanding of Parkinson's disease and other basal ganglia diseases
The direct pathway, sometimes known as the direct pathway of movement, is a neural pathway within the central nervous system (CNS) through the basal ganglia which facilitates the initiation and execution of voluntary movement. [1] It works in conjunction with the indirect pathway.
The CBGTC loop has been implicated in many diseases. For example, in Parkinson's disease, degeneration of dopaminergic neurons leading to decreased activity of the excitatory pathway is thought to result in hypokinesia, [15] and in Huntington's disease, degeneration of GABAergic neurons driving the inhibitory pathway is thought to result in the jerky body movements. [2]