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Hypomimia (masked faces, masking of faces, mask-like facial expression), a medical sign, is a reduced degree of facial expression. It can be caused by motor impairment (for example, weakness or paralysis of the facial muscles ), as in Parkinson's disease , or by other causes, such as psychological or psychiatric factors (for example, if a ...
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions.
Parkinson's typically manifests in individuals over 60, with about one percent affected. In those younger than 50, it is termed "early-onset PD". No cure for Parkinson's is known, and treatment focuses on alleviating symptoms. Initial treatment typically includes L-DOPA, MAO-B inhibitors, or dopamine agonists.
Parkinson’s is “a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination,” per the National Institute of ...
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Parkinson-plus syndrome; Parkinson's disease; Parkinson's Disease (journal) Parkinson's disease and gut-brain axis; Research in Parkinson's disease; Parkinsonian gait; Parkinsonism; Pathophysiology of Parkinson's disease; PD-0298029; Prasinezumab
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