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Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Skip to main content. 24/7 Help. For premium support please call: ...
If metformin is causing GI side effects such as diarrhea or bloating, first try reducing the dose and taking it just once a day instead of twice a day, Dr. Gupta suggests.
Your healthcare provider may give you additional instructions depending on what you’re taking metformin for — i.e., as a diabetes medication or a weight loss treatment.
Sterne was the first to try metformin on humans for the treatment of diabetes; he coined the name "Glucophage" (glucose eater) for the medication and published his results in 1957. [161] [168] Metformin became available in the British National Formulary in 1958. It was sold in the UK by a small Aron subsidiary called Rona. [169]
Since alpha-glucosidase inhibitors prevent the degradation of complex carbohydrates into glucose, the carbohydrates will remain in the intestine. In the colon, bacteria will digest the complex carbohydrates, thereby causing gastrointestinal side effects such as flatulence and diarrhea. Since these effects are dose-related, it is generally ...
The most common side effect is diarrhea and dyspepsia, occurring in up to 30% of patients. The most important and serious side effect is lactic acidosis, therefore metformin is contraindicated in advanced chronic kidney disease. Kidney function should be assessed before starting metformin.
Metformin is the most commonly prescribed oral drug for diabetes. Of course, if you or a loved one receives treatment for diabetes, you probably already knew this.
There’s been lots of attention on type 2 diabetes drugs recently, especially since they might also be able to support weight loss. Whether you have type 2 diabetes or obesity, you may have heard ...