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A chimera can have two different colored eyes just like any two siblings can—because each cell has different eye color genes. A mosaic can have two different colored eyes if the DNA difference happens to be in an eye-color gene. There are many other possible reasons for having two different-colored eyes.
They can have blue (including aqua), golden (including shades of brown, copper, amber, yellow, and hazel), or green eyes. Furthermore, odd-eyes are allowed; with one of each colour or multiple colours within one eye. [7] [8] The odd-eyed Khao Manee is the rarest variety.
Blue eyes are also found in parts of Western Asia, most notably in Afghanistan, Syria, Iraq, and Iran. [53] In Estonia, 99% of people have blue eyes. [54] [55] In Denmark in 1978, only 8% of the population had brown eyes, though through immigration, today that number is about 11%. [55] In Germany, about 75% have blue eyes. [55]
Central heterochromia, blue with brown. Central heterochromia is also an eye condition where there are two colors in the same iris; but the arrangement is concentric, rather than sectoral. The central (pupillary) zone of the iris is a different color than the mid-peripheral (ciliary) zone.
According to F.M Savina of the Paris Foreign Missionary Society, the appearance of the Miao was "pale yellow in complexion, almost white, their hair is often light or dark brown, sometimes even red or corn-silk blond, and a few even have pale blue eyes". [35] A phenotype study of Hmong people show they are sometimes born with red hair. [36]
Blue eyes are also found in southern Europe, Central Asia, South Asia, North Africa and West Asia. [58] [59] Approximately 8% to 10% of the global population have blue eyes. [35] A 2002 study found that the prevalence of blue eye color among the white population in the United States to be 33.8% for those born from 1936 through 1951.
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin.The blue colour is caused by melanocytes, melanin-containing cells, that are usually located in the surface of the skin (the epidermis), but are in the deeper region (the dermis) in the location of the spot. [6]
Melanin in the eyes, in the iris and choroid, helps protect from ultraviolet and high-frequency visible light; people with blue, green, and grey eyes are more at risk of sun-related eye problems. Furthermore, the ocular lens yellows with age, providing added protection.