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Due to its sympathomimetic effects, pseudoephedrine is a vasoconstrictor and pressor agent (increases blood pressure), a positive chronotrope (increases heart rate), and a positive inotrope (increases force of heart contractions). [18] [1] [22] [19] [20] The influence of pseudoephedrine on blood pressure at clinical doses is controversial.
Pseudoephedrine acts indirectly on the adrenergic receptor system, whereas phenylephrine and oxymetazoline are direct agonists. The effects are not limited to the nose, and these medicines may cause hypertension (high blood pressure) through vasoconstriction; it is for this reason that people with hypertension are advised to avoid them. Most ...
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Ephedrine is a non-catecholamine sympathomimetic with cardiovascular effects similar to those of adrenaline/epinephrine: increased blood pressure, heart rate, and contractility. Like pseudoephedrine it is a bronchodilator, with pseudoephedrine having considerably less effect. [19] [20]
For example, a blood pressure above 120/80 is too high, and every point higher takes a toll on the body because the pressure pounds through the arteries 24/7, never resting and the negative ...
Sympathomimetic drugs are used to treat cardiac arrest and low blood pressure, or even delay premature labor, among other things. These drugs can act through several mechanisms, such as directly activating postsynaptic receptors , blocking breakdown and reuptake of certain neurotransmitters, or stimulating production and release of catecholamines.
High blood pressure emergency symptoms. Headaches and nosebleeds can be symptoms of a hypertensive emergency or crisis. If your blood pressure is 180/120 mm Hg or higher and you have these ...
High blood pressure is when the force of blood against your artery walls is too high when your heart beats. If left untreated, this force can damage the blood vessels and cause heart disease ...