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An adult heart has a mass of 250–350 grams (9–12 oz). [17] The heart is often described as the size of a fist: 12 cm (5 in) in length, 8 cm (3.5 in) wide, and 6 cm (2.5 in) in thickness, [8] although this description is disputed, as the heart is likely to be slightly larger. [18]
In a healthy heart all activities and rests during each individual cardiac cycle, or heartbeat, are initiated and orchestrated by signals of the heart's electrical conduction system, which is the "wiring" of the heart that carries electrical impulses throughout the body of cardiomyocytes, the specialized muscle cells of the heart.
Intravascular ultrasound image of a coronary artery (left), with color-coding on the right, delineating the lumen (yellow), external elastic membrane (blue) and the atherosclerotic plaque burden (green). The percentage stenosis is defined as the area of the lumen (yellow) divided by the area of the external elastic membrane (blue) times 100.
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Coronary artery disease (CAD) or ischemic heart disease are the terms used to describe narrowing of the coronary arteries. [8] As the disease progresses, plaque buildup can partially block blood flow to the heart muscle. Without enough blood supply , the heart is unable to work properly, especially under increased stress.
Humans have a four-chambered heart consisting of the right and left atrium, and the right and left ventricle. The atria are the two upper chambers which pump blood to the two lower ventricles. The right atrium and ventricle are often referred to together as the right heart, and the left atrium and ventricle as the left heart.
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A slow heart rate of 60 or less beats per minute is defined as bradycardia. A fast heart rate of more than 100 beats per minute is defined as tachycardia. An arrhythmia is defined as one that is not physiological such as the lowered heart rate that a trained athlete may naturally have developed; the resting heart rates may be less than 60 bpm.