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Kidney stones are primarily composed of calcium salts, with the most common being calcium oxalate (70-80%), followed by calcium phosphate and uric acid. When urine contains high concentrations of these ions, they can form crystals and eventually stones. [41] The formation of kidney stones occurs in three main phases: [41]
For kidney stone prevention or alkalinization, it is most often accompanied by mineral(s) sodium or potassium. Less frequently, magnesium citrate may be included. [2] This results in compounds like Trimagnesium citrate, [5] Tripotassium citrate [6] [7] [8] and Trisodium citrate: [9] Potassium citrate: K 3 C 6 H 5 O 7 or C 6 H 5 K 3 O 7 [10 ...
Citric acid/potassium-sodium citrate is a drug used in the treatment of metabolic acidosis (a disorder in which the blood is too acidic). It is made up of citrate (the weak base of citric acid), a sodium cation and potassium cation. It can also be used for the treatment of kidney stones [1] by treating hypocitraturia. [2]
Dent's disease (or Dent disease) is a rare X-linked recessive inherited condition that affects the proximal renal tubules [1] of the kidney.It is one cause of Fanconi syndrome, and is characterized by tubular proteinuria, excess calcium in the urine, formation of calcium kidney stones, nephrocalcinosis, and chronic kidney failure.
Changes in urination are also kidney stone hallmarks, according to Dr. Ivan Porter, MD, Vice Chair, Division of Nephrology and Hypertension, Department of Medicine; Assistant Dean, Mayo Clinic ...
Sodium citrate is used to prevent donated blood from clotting in storage, and can also be used as an additive for apheresis to prevent clots forming in the tubes of the machine. By binding with calcium ions in the blood it prevents the process of coagulation. It is also used as an anticoagulant for laboratory testing, in that blood samples are ...
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