Search results
Results From The WOW.Com Content Network
A binding study assessed PCP at 56 sites including neurotransmitter receptors and transporters and found that PCP had K i values of >10,000 nM at all sites except the dizocilpine (MK-801) site of the NMDA receptor (K i = 59 nM), the σ 2 receptor (K i = 136 nM), and the serotonin transporter (K i = 2,234 nM). [38]
Pentachlorophenol (PCP) is an organochlorine compound used as a pesticide and a disinfectant. First produced in the 1930s, it is marketed under many trade names. [5] It can be found as pure PCP, or as the sodium salt of PCP, the latter of which dissolves easily in water. It can be biodegraded by some bacteria, including Sphingobium ...
Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine) the synthesis of which was first published in 1907. PCP itself was discovered in 1926 but not ...
During the 5-year follow-up, 461 people developed dementia, and 2,576 people developed cognitive impairment. After adjusting for sociodemographic and lifestyle factors, family history of dementia ...
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.
2C-P produces intense hallucinogenic, psychedelic, and entheogenic effects including open eye visualizations and closed-eye visualizations. [2] It can have a very slow onset if ingested, and peak effects reportedly do not occur for 3 to 5 hours. [2] The peak lasts for five to ten hours, with the overall experience lasting up to 20 hours.
An assortment of several designer drugs. Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal.
January 1, 2025 at 7:31 AM. The odds are high you’ve had a cough before in your life, but each time can throw you for a loop. Even though you’ve been through this, it can be hard to know when ...