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Mepyramine, also known as pyrilamine, is a first-generation antihistamine, targeting the H 1 receptor as an inverse agonist. [1] Mepyramine rapidly permeates the brain, often causing drowsiness. [2] It is often sold as a maleate salt, pyrilamine maleate.
Pyrilamine maleate 15 mg (antihistamine) The "Extended Relief" formulation consists of: Naproxen sodium 220 mg (NSAID, pain reliever/fever reducer) The "Teen" formulation consists of: Acetaminophen 500 mg (pain reliever) Pamabrom 25 mg ; The "Liquid Gels" (Labeled MAXIDOL) [8] formulation consists of: Ibuprofen 200 mg (NSAID, pain reliever)
Mepyramine (pyrilamine) Chloropyramine; Antazoline; Tripelennamine; Ethanolamines: Diphenhydramine was the prototypical agent in this group. Significant anticholinergic adverse effects, as well as sedation, are observed in this group but the incidence of gastrointestinal adverse effects is relatively low. [4] [15] Diphenhydramine; Carbinoxamine ...
In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine.It can be used in the treatment of asthma, hay fever, rhinitis, and urticaria, but is now less common as it has been replaced by newer antihistamines.