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The medial forebrain bundle may serve as a target in treating treatment-resistant depression. [8] Since the MFB connects areas of the brain which are involved with motivated behavior, mood regulation, and antidepressant response the stimulation of the MFB through deep brain stimulation could be an effective form of treatment.
The lateral hypothalamus is a portion of the hypothalamus, and brain stimulation to this area at the level of the medial forebrain bundle produces the highest response rates and subsequently the highest reward potency in rodents. Lesions in this region or along its boundary cause a loss of positive drive-reward behaviors as well as all other ...
A small ascending dorsal serotonergic pathway arising from the ventral and dorsal superior raphe nuclei initially travels in the DLF, with some of its fibres terminating in the periaqueductal gray of the midbrain, and the posterior hypothalamus; the majority of its fibers however pass beyond the DLF in the medial forebrain bundle, here uniting ...
The medial longitudinal fasciculus (MLF) is a prominent bundle of nerve fibres which pass within the ventral/anterior portion of periaqueductal gray of the mesencephalon (midbrain). [1] It contains the interstitial nucleus of Cajal , responsible for oculomotor control, head posture, and vertical eye movement.
The mesolimbic pathway and its positioning in relation to the other dopaminergic pathways. The mesolimbic pathway is a collection of dopaminergic (i.e., dopamine-releasing) neurons that project from the ventral tegmental area (VTA) to the ventral striatum, which includes the nucleus accumbens (NAcc) and olfactory tubercle. [9]
Medial parabrachial nucleus; Lateral parabrachial nucleus; Subparabrachial nucleus (Kölliker-Fuse nucleus) Pontine respiratory group; Superior olivary complex. Medial superior olive; Lateral superior olive; Medial nucleus of the trapezoid body; Paramedian pontine reticular formation; Parvocellular reticular nucleus; Caudal pontine reticular ...
A neural pathway connects one part of the nervous system to another using bundles of axons called tracts. The optic tract that extends from the optic nerve is an example of a neural pathway because it connects the eye to the brain; additional pathways within the brain connect to the visual cortex.
Other axons arising from these cells descend through the medial forebrain bundle to terminate in a region dorsal to the interpeduncular nucleus. The lateral septum is a relay center for connections from the CA3 of the hippocampus to the ventral tegmental area.