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Ichthyosis (also named fish scale disease) [1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive , autosomal or X-linked ). [ 3 ]
The condition is not life-threatening; the impact on the patient, if it is a mild case, is generally restricted to mild itching and the social impact of having skin with an unusual appearance. People with mild cases have symptoms that include scaly patches on the shins, fine white scales on the forearms and upper arms, and rough palms.
After as little as two weeks of daily oral isotretinoin, fissures in the skin can heal, and plate-like scales can nearly resolve. Improvement in the eclabium and ectropion can also be seen in weeks. Children who survive the neonatal period usually develop a less severe phenotype, resembling a severe congenital ichthyosiform erythroderma .
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Jeff Karp had just undergone his first full-body routine skin cancer check in the spring of 2022 and was about to walk out of the exam room, when, on a whim, the 47-year-old decided to ask his ...
Man diagnosed with basal cell carcinoma, treated with cream after his first routine skin check with a dermatologist. Harvard scientist's 'doorknob' question leads to skin cancer diagnosis Skip to ...
neglected squamous cell carcinoma skin of scalp Advanced squamous cell carcinoma, excision specimen. Note invasion subcutaneous tissue. Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma.
Progressive itching that intensifies over a few weeks, accompanied by a yellowing of the eyes and skin, can be a sign of pancreatic cancer. Emergency medicine: Man's itching result of pancreatic ...