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Alezzandrini syndrome is a very rare syndrome characterized by a unilateral degenerative retinitis, followed after several months by ipsilateral vitiligo on the face and ipsilateral poliosis. [1]: 864 [2] Deafness may also be present. [1]: 864 [3]
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
Poliosis circumscripta, commonly referred to as a "white forelock", is a condition characterized by localized patches of white hair due to a reduction or absence of melanin in hair follicles. Although traditionally associated with the scalp, poliosis can affect any hairy area on the body, including eyebrows, eyelashes, and beards.
Uveitis with poliosis of the eyelashes. The disease is characterised by bilateral diffuse uveitis, with pain, redness and blurring of vision.The eye symptoms may be accompanied by a varying constellation of systemic symptoms, such as auditory (tinnitus, [6] vertigo, [6] and hypoacusis), neurological (meningismus, with malaise, fever, headache, nausea, abdominal pain, stiffness of the neck and ...
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He diagnosed Jackson with lupus that year, [12] and with vitiligo in 1986. [13] Vitiligo's drastic effects on the body can cause psychological distress. Jackson used fair-colored makeup, [3] and possibly skin-bleaching prescription creams, [4] to cover up the uneven blotches of color caused by the illness.
Nevus depigmentosus is a loss of pigment in the skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to growth of the body.
Piebaldism is unrelated to conditions such as vitiligo or poliosis. Although "partial albinism" is a synonym for piebaldism, [ 3 ] it is a fundamentally different condition from true albinism . The vision problems associated with albinism are not usually present as eye pigmentation is normal.
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