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Plummer–Vinson syndrome (also known as Paterson–Kelly syndrome [1] or Paterson–Brown-Kelly syndrome in the UK [2]) is a rare disease characterized by dysphagia (difficulty swallowing), iron-deficiency anemia, glossitis (inflammation of the tongue), cheilosis (cracking at the corners of the mouth), and esophageal webs (thin membranes in the esophagus that can cause obstruction). [1]
Dysgeusia (usually a bitter or metallic taste) is present in about 60% of people with BMS, a factor which led to the concept of a defect in sensory peripheral neural mechanisms. [12] Changes in the oral environment, such as changes in the composition of saliva, may induce neuropathy or interruption of nerve transduction.
The distortion in the sense of taste is the only symptom, and diagnosis is usually complicated since the sense of taste is tied together with other sensory systems. Common causes of dysgeusia include chemotherapy, asthma treatment with albuterol, and zinc deficiency.
Here are the common causes of a metallic taste in mouth, and how you can get rid of it. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ...
Iron deficiency is more common in women than in men, and it often goes undiagnosed. ... “Iron is a metal that is very abundant on the earth and unfortunately it's also one of the most common ...
Iron deficiency can also cause shortness of breath, and amplify the symptoms of any chronic condition, such as depression. It can also have an affect on your mood, ability to focus and sleep quality .
They are mainly observed in the Plummer–Vinson syndrome, [3] which is associated with chronic iron deficiency anemia.One in 10 patients with Plummer-Vinson syndrome will eventually develop squamous cell carcinoma of the esophagus, [4] but it is unclear if esophageal webs in and of themselves are a risk factor.
Dysgeusia – altered taste sensation (e.g., a metallic taste) [1] and dysosmia, altered sense of smell. [3] Intraoral halitosis [1] – possibly due to increased activity of halitogenic biofilm on the posterior dorsal tongue (although dysgeusia may cause a complaint of nongenuine halitosis in the absence of hyposalivation).
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