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Liquid chromatography–mass spectrometry (LC–MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). Coupled chromatography – MS systems are popular in chemical analysis because the individual capabilities ...
Both, the first mass analyzer and the collision cell are continuously exposed to ions from the source, in a time independent manner. [4] It is once the ions move into the third mass analyzer that time dependence becomes a factor. [4] The first quadrupole mass filter, Q1, is the primary m/z selector after the sample leaves the ionization source.
Narrow-bore columns (1–2 mm) are used for applications when more sensitivity is desired either with special UV-vis detectors, fluorescence detection or with other detection methods like liquid chromatography-mass spectrometry. Capillary columns (under 0.3 mm) are used almost exclusively with alternative detection means such as mass spectrometry.
Liquid chromatography-inductively coupled plasma mass spectrometry (LC-ICP-MS), Gas chromatography-inductively coupled plasma mass spectrometry (GC-ICP-MS), Laser ...
Supercritical fluid chromatography; Electrophoresis; Ligand binding assays. Dual polarisation interferometry; ELISA (Enzyme-linked immunosorbent assay) MIA (magnetic immunoassay) RIA (radioimmunoassay) Mass spectrometry; Nuclear magnetic resonance; The most frequently used techniques are: liquid chromatography coupled with tandem mass ...
Indianapolis Museum of Art conservation scientist performing liquid chromatography–mass spectrometry. Similarly to gas chromatography MS (GC-MS), liquid chromatography-mass spectrometry (LC/MS or LC-MS) separates compounds chromatographically before they are introduced to the ion source and mass spectrometer.