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Eosinophilic cellulitis, also known as Wells' syndrome (not to be confused with Weil's disease), is a skin disease that presents with painful, red, raised, and warm patches of skin. [2] The rash comes on suddenly, lasts for a few weeks, and often repeatedly comes back. [ 2 ]
The classification of all these eosinophilic cellulitis reactions, whether triggered by a mosquito bite, triggered by some other agent, or apparently untriggered, is argued; [3] it has been proposed that eosinophilic cellulites is not a distinct clinical entity but rather a set of skin reactions in various diagnosed or yet-to be diagnosed ...
Eosinophilic cutaneous conditions encompass a wide variety of diseases that are characterized histologically by the presence of eosinophils in the inflammatory infiltrate and/or evidence of eosinophil degranulation.
Eosinophilic cellulitis (Wells' syndrome) Eosinophilic fasciitis (Shulman's syndrome) Eosinophilic granuloma; Eosinophilic granulomatosis with polyangiitis; Eosinophilic pustular folliculitis of infancy (eosinophilic pustular folliculitis in infancy, infantile eosinophilic pustular folliculitis, neonatal eosinophilic pustular folliculitis)
Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5 × 10 8 /L (500/μL). [1] Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 10 9 /L (i.e. 1,500/μL).
For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. [ 6 ] [ 7 ] Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. [ 8 ]
Eosinophilic vasculitis is a cutaneous condition characterized by an inflammation of blood vessels and the presence of eosinophils. [1] See also
Eosinophilic dermatosis is a form of dermatosis characterized by a preponderance of eosinophils in the dermis or epidermis. [ 1 ] Although it does not always imply a specific etiology, it is still commonly used as a classification in dermatology when more information about the condition is not known.