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Tamsulosin, sold under the brand names including Flomax and Contiflo, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones. [6] [7] [8] The evidence for benefit with a kidney stone is better when the stone is larger. [8] Tamsulosin is taken by mouth. [6]
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
Patients can also attempt to avoid products and medications with anticholinergic properties that may exacerbate urinary retention symptoms of BPH, including antihistamines, decongestants, opioids, and tricyclic antidepressants; however, changes in medications should be done with input from a medical professional.
Terazosin was the first long-lasting alpha 1 blocker approved by FDA to treat BPH. Doxazosin and Tamsulosin were approved after. The first-line treatment choice today to treat BPH is tamsulosin. It is not better tolerated, nor does it have greater efficacy than the previous drugs, however, it requires minimal dose titration in comparison.
This was shown in the SPCG-6 Tooltip Scandinavian Prostate Cancer Group 6 substudy (n=1218) of the EPC programme, in which overall survival was significantly worse in the 150 mg/day bicalutamide monotherapy group compared to the placebo/standard care group (HR Tooltip hazard ratio = 1.47; 95% CI Tooltip confidence interval = 1.06–2.03). [81]
When it comes to diuretics, which cause you to shed excess fluid, if you are also sweating a lot, he said this “can worsen [dehydration] by further removing sodium and water from the body which ...
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