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Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Does Metformin Cause Diarrhea?
The most common side effects of metformin include: Diarrhea. Nausea. Vomiting. Upset stomach. Weakness. ... Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset ...
Metformin can have side effects, though they’re usually mild. The most common side effects are gastrointestinal (everyone’s favs: diarrhea, bloating, stomach pain, gas, indigestion and ...
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Apparently, the (unknown) mechanism of induction of diarrhea caused by metformin is different than for ordinary diarrhea. A distinguishing feature of metformin-induced diarrhea is that it is associated with strong, painful intestinal cramping that occurs irrespective of what is in the colon. The initial bowel motions may be quite solid.
The most common side effect is diarrhea and dyspepsia, occurring in up to 30% of patients. The most important and serious side effect is lactic acidosis, therefore metformin is contraindicated in advanced chronic kidney disease. Kidney function should be assessed before starting metformin.
Diarrhea. Flatulence. Asthenia (feeling weak or lacking energy) Stomach pain. Headache. Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication ...
Though it’s considered safe, up to 30 percent of people who take metformin experience gastrointestinal side effects like nausea, vomiting, and diarrhea. Naltrexone-bupropion .