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A leprostatic agent is a drug that interferes with proliferation of the bacterium that causes leprosy. [1] [2] The following agents are leprostatic agents: [3] acedapsone; clofazimine; dapsone; desoxyfructo-serotonin; diucifon; ethionamide; rifampicin; rifapentine; sulfameter; thalidomide; Leprosy is a chronic infectious disease caused by ...
Mycobacterium leprae, the causative agent of leprosy, was discovered by G. H. Armauer Hansen in Norway in 1873, making it the first bacterium to be identified as causing disease in humans. [2] [25] Hansen observed a number of nonrefractile small rods in unstained tissue sections. The rods were not soluble in potassium lye, and they were acid ...
A goal of the WHO is to "eliminate leprosy," and in 2016 the organization launched "Global Leprosy Strategy 2016–2020: Accelerating towards a leprosy-free world". [ 168 ] [ 169 ] Elimination of leprosy is defined as "reducing the proportion of (people with) leprosy in the community to very low levels, specifically to below one case per 10,000 ...
Leprosy, sometimes known as Hansen's disease, is an infectious disease caused by Mycobacterium leprae, an aerobic, acid-fast, rod-shaped mycobacterium. The modern term for the disease is named after the discoverer of the bacterium, Gerhard Armauer Hansen .
Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
Hydnocarpus wightiana seed oil has been widely used in traditional Indian medicine, especially in Ayurveda, and in Chinese traditional medicine for the treatment of leprosy. It entered early Western medicine in the nineteenth century before the era of sulfonamides and other antibiotics for the treatment of several skin diseases and leprosy. [4]
Mycobacterium lepromatosis is an aerobic, acid-fast bacillus (AFB), and the second known causative agent of Hansen's disease . It was discovered in 2008. It was discovered in 2008. Analysis of the 16S rRNA gene confirms that the species is distinct from Mycobacterium leprae .
They concluded that a single dose of a combination of rifampicin, ofloxacin and minocycline is an acceptable and cost-effective alternative regimen for the treatment of single-lesion paucibacillary leprosy and the duration of the standard regimen for multibacillary leprosy could be shortened to 12 months.