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An acinus (/ ˈ æ s ɪ n ə s /; pl.: ... where the secretion is produced, is acinar in form, as is the alveolar sac containing multiple alveoli in the lungs ...
Almost any type of lung tumor or lung cancer can compress the alveoli and reduce gas exchange capacity. In some cases the tumor will fill the alveoli. [33] Cavitary pneumonia is a process in which the alveoli are destroyed and produce a cavity. As the alveoli are destroyed, the surface area for gas exchange to occur becomes reduced.
The conducting zone of the respiratory tract ends at the terminal bronchioles when they branch into the respiratory bronchioles. This marks the beginning of the terminal respiratory unit called the acinus which includes the respiratory bronchioles, the alveolar ducts, alveolar sacs, and alveoli. [27] An acinus measures up to 10 mm in diameter. [28]
A lobule of the lung enclosed in septa and supplied by a terminal bronchiole that branches into the respiratory bronchioles. Each respiratory bronchiole supplies the alveoli held in each acinus accompanied by a pulmonary artery branch. The pulmonary lobule is the portion of the lung ventilated by one bronchiole.
The alveoli are tiny air sacs in the lungs where gas exchange takes place. The mean number of alveoli in a human lung is 480 million. [11] When the diaphragm contracts, a negative pressure is generated in the thorax and air rushes in to fill the cavity. When that happens, these sacs fill with air, making the lung expand.
Panlobular emphysema, also called panacinar emphysema, affects all of the alveoli in a lobule, and can involve the whole lung or mainly the lower lobes. [ 18 ] [ 24 ] This type of emphysema is associated with alpha-1 antitrypsin deficiency (A1AD or AATD), and Ritalin lung , [ 24 ] and is not related to smoking.
The zones of the lung divide the lung into four vertical regions, based upon the relationship between the pressure in the alveoli (PA), in the arteries (Pa), in the veins (Pv) and the pulmonary interstitial pressure (Pi): Zone 1: PA > Pa > Pv; Zone 2: Pa > PA > Pv; Zone 3: Pa > Pv > PA; Zone 4: Pa > Pi > Pv > PA
Emphysema. Collateral ventilation is a back-up system of alveolar ventilation that can bypass the normal route of airflow when airways are restricted or obstructed. The pathways involved include those between adjacent alveoli (pores of Kohn), between bronchioles and alveoli (canals of Lambert), and those between bronchioles (channels of Martin).