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Amenorrhea or amenorrhoea is the absence of a menstrual period in a female who has reached reproductive age. [1] Physiological states of amenorrhoea are most commonly seen during pregnancy and lactation ( breastfeeding ).
FHA can have long and short term consequences in a patient's reproductive development and fertility. Anovulation and amenorrhea is the characteristic feature of FHA. [3] If hypoestrogenism and impaired HPO axis occurs during puberty, primary amenorrhea occurs. [4]
Common side effects include menstrual disturbances such as absence of periods, abdominal pain, and headaches. [10] More serious side effects include bone loss, blood clots, allergic reactions, and liver problems. [10] Use is not recommended during pregnancy as it may harm the baby. [10]
Hypoestrogenism is most commonly found in women who are postmenopausal, have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods). Hypoestrogenism includes primarily genitourinary effects, including thinning of the vaginal tissue layers and an increase in vaginal pH.
In addition to the alteration of menstrual periods and infertility, chronic anovulation can cause or exacerbate other long-term problems, such as hyperandrogenism or osteopenia. It plays a central role in the multiple imbalances and dysfunctions of polycystic ovary syndrome .
6 Potential Long-Term Effects of Ozempic. You may have heard about — or maybe even experienced — the short-term side effects of Ozempic® — such as nausea, vomiting, constipation, and diarrhea.
Mothers who breastfed exclusively longer showed a longer span of lactational amenorrhea, ranging from an average of 5.3 months in mothers who breastfed exclusively for only two months to an average of 9.6 months in mothers who did so for six months. [10] Another factor shown to affect the length of amenorrhea was the mother's age.
Ozempic side effects that are more common in females vs. males include nausea, vomiting, dizziness, and headache. Females also tend to experience more weight loss on Ozempic, as well as a larger ...