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A Trypanosomiasis vaccine is a vaccine against trypanosomiasis. No effective vaccine currently exists, but development of a vaccine is the subject of current research. The Gates Foundation has been involved in funding research conducted by the Sabin Vaccine Institute and others. [1] There are many obstacles to development of such a vaccine.
Serological testing is also common. One common way in which trypanosomiasis can be diagnosed in humans is through the detection of antibodies against trypanosomes made by host organisms. [6] One commonly used antibody test which operated based on this principle is the card agglutination test, C.A.T.T. for T. gambiense.
African trypanosomiasis is an insect-borne parasitic infection of humans and other animals. [3]Human African trypanosomiasis (HAT), also known as African sleeping sickness or simply sleeping sickness, is caused by the species Trypanosoma brucei. [3]
Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by Trypanosoma cruzi. It is spread mostly by insects in the subfamily Triatominae, known as "kissing bugs". The symptoms change throughout the infection.
Animal trypanosomiasis is transmitted by a dozen species of Glossina. [90] In later stages of a T. brucei infection of a mammalian host the parasite may migrate from the bloodstream to also infect the lymph and cerebrospinal fluids. It is under this tissue invasion that the parasites produce the sleeping sickness.
Scabies (also sometimes known as the seven-year itch) is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite Sarcoptes scabiei, variety hominis. The word is from Latin: scabere, lit. 'to scratch'. The most common symptoms are severe itchiness and a pimple -like rash. Occasionally, tiny burrows may appear on the skin. In a first-ever infection, the infected person usually ...
Trypanosoma is a genus of kinetoplastids (class Trypanosomatidae [1]), a monophyletic [2] group of unicellular parasitic flagellate protozoa.Trypanosoma is part of the phylum Euglenozoa. [3]
An efficient and practical intervention (such as a vaccine or antibiotic) must be available to interrupt transmission. Studies of measles in the pre-vaccination era led to the concept of the critical community size , the minimal size of the population below which a pathogen ceases to circulate. [ 3 ]