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John Wayne Mason, M.D. (February 9, 1924 – March 4, 2014) was an American physiologist [1] and researcher who specialized in the interplay between human emotions and the endocrine system. [2] Mason is regarded as an international leader and theoretician in the field of stress research, [ 3 ] where he was one of the field's most prominent ...
(A stressor is a chemical or biological agent, environmental condition, external stimulus or an event seen as causing stress to an organism.) Selye initially (c. 1940s) called this the "general adaptation syndrome" (at the time it was also called "Selye's syndrome"), but he later rebaptized it with the simpler term "stress response".
Within the branch of materials science known as material failure theory, the Goodman relation (also called a Goodman diagram, a Goodman-Haigh diagram, a Haigh diagram or a Haigh-Soderberg diagram) is an equation used to quantify the interaction of mean and alternating stresses on the fatigue life of a material. [1]
The diathesis-stress model, also known as the vulnerability–stress model, is a psychological theory that attempts to explain a disorder, or its trajectory, as the result of an interaction between a predispositional vulnerability, the diathesis, and stress caused by life experiences.
A study about stress effects on female songbird’s response to sexual signal for mating indicated that the response to this specific signal can be impaired if the female is exposed to developmental stress. Behavioural changes as a result from developmental stress impairs neural responses to sexual signals, which reduces mating. [5]
Perseverative cognition is involved with a “stress-disease link". [1] Further, it is the thinking about the stress, or rather the obsessing over it, that establishes a link between stress and disease. Perseverative cognition also focuses on the effects that worrying over anticipated events have on the physical body and mind. [2]
The integrated stress response can be triggered within a cell due to either extrinsic or intrinsic conditions. Extrinsic factors include hypoxia, amino acid deprivation, glucose deprivation, viral infection and presence of oxidants. The main intrinsic factor is endoplasmic reticulum stress due to the accumulation of unfolded proteins.
Extreme exposure to such toxic stress can result in the stress response system becoming more highly sensitized to stressful events, producing increased wear and tear on physical systems through over-activation of the body's stress response. This wear and tear increases the later risk of various physical and mental illnesses. [15]